Monday, 7 July 2025

Glucose monitors: useful or not?

A couple of months ago I had the opportunity to wear a Lingo glucose monitor for 2 weeks. I've often over the years had times when I've craved carbs for an energy boost that when eaten then create a spike then a crash and more craving.....the 'spike-crash cycle'. I also used to get "hangry" - that hunger and irritability/anger that stems from a drop in glucose and creates a perfect storm for our hormones. Since my diagnosis and changing my nutrition this has been much much less so...almost not occurring....but occasionally it has surprised me - hence the interest in the monitor.

Was it worth it? 

I did learn stuff - more of that in a mo....before then by coincidence the week after I finished I came across a new study that calls into question the usefulness of these blood-glucose plans for folks without diabetes.

In two controlled studies using 30 participants, researchers found only weak-to-moderate correlations between the same meals eaten a week apart. This means your body's response to your morning porridge might be completely different from meal to meal. Which if true, makes basing food choices on how you react to one meal pretty pointless (and even dangerous!). See more at: https://examine.com/research-feed/study/1jjKq1/?

Glucose spike dangers?

So glucose spikes are when you have more glucose in your bloodstream than your cells can take up. Some degree of rise is completely normal but it is the dips or crashes that can impact on long term health - research suggesting not least an increased risk for developing insulin resistance, type 2 diabetes, and cardiovascular issues.

Serious sugar spike material

Sugar warnings?

Sugar and carbohydrates are the quickest to be converted to glucose - any not being used gets stored in the body. It is when it is too concentrated in the blood that it is called a glucose spike or blood sugar spike. 

Many of us with cancer have heard the 'warnings' that sugar can impact cancer - but also hear the NHS and and others saying that it is all 'a myth' - see for example this piece by Cancer Research UK here. They write: "All of our healthy cells need glucose too, and there’s no way of telling our bodies to let healthy cells have the glucose they need without also giving it to cancer cells. And cancer cells also need lots of other nutrients too, like amino acids and fats; it’s not just sugar they crave. There’s no evidence that following a “sugar-free” diet lowers the risk of getting cancer, or that it boosts the chances of surviving if you are diagnosed." 

The article goes on to note the concerns about sugar and obesity and the links between being overweight and cancer. However I do not think this takes seriously the growing evidence around the negative impact of refined sugar.

Read this blog by Robin Daly looking at this issue and evidence - he notes the views of NHS oncologist Professor Thomas: "Prof Thomas makes the point that, given the sheer volume of good evidence pointing towards dietary refined sugars and carbohydrates as both a source and driver of cancer, along with the catastrophic way that the grim reaper, cancer, is scything its way through developed nations around the globe, a zero-cost, safe intervention such as reducing intake of refined foods should be seen as eminently worth trying. Making utterly confident pronouncements about the absence of a relationship between sugar and cancer depends entirely on a totally suspect system that seeks to portray evidence as a binary ‘evidence/no evidence’ scenario, rather than as a more nuanced sliding scale of ‘more evidence’, ‘better evidence’."

Also see a useful and totally sensible discussion of sugar on this video of a Yes to Life Forum I helped host in October 2020 with nutritionist Kirstin Chick here.

Other factors

Spikes can also be caused by other factors like poor sleep, dehydration, caffeine, certain medications or stress - also during intense exercise. However it is most often eating carbs/sugar. 

Mild, dark and black tahini on toast
Some learning

My own monitor showed how my blood sugar spiked particularly after carbs - even just two oatcakes as a snack in the afternoon had a surprisingly large spike. In contrast the gluten-free toast with tahini's as part of a breakfast with a walk afterwards had less of a spike. Reducing snacking helped - and ensuring I had protein with every meal.

You will see the chart from my first week that I was missing the target but learning about some of the impacts....one noticeable improvement was going for a short walk after my evening meal.

The monitor I used was Lingo - others available - their app recorded great info and some useful tips but you need to download it as it seems to disappear from the app after the 2 weeks. Anyhow this rather basic info was from one of their blogs

How to avoid a glucose spike 

There are many ways to avoid a glucose spike naturally, and the best method is to be thoughtful with your food choices. Limit foods that are common sources of spikes such as refined carbohydrates, sugars, and sugary beverages, and instead opt for more complex carbohydrates that have fibre such as vegetables, fresh fruit, brown rice, quinoa, and whole grain bread. Even better, pair your carbohydrates with a source of protein and/or fat for a macronutrient-balanced option. 

Other lifestyle habits that can help keep your glucose steady include getting quality sleep, staying physically active, drinking plenty of water, managing stress, and limiting alcohol.

A lot of this is pretty obvious but I guess for me it was still a useful exercise in helping me think about meals again - over the years since diagnosis some good habits slip a little - it was a good reminder even if the research noted above suggests they may not be so useful. Anyone with any questions re this should speak with their medical team - this blog was just my experience.

See blog on Ultra-processed foods being recommended by NHS (??!): https://myunexpectedguide.blogspot.com/2023/04/ultra-processed-foods-recommended-by.html

See blog on best nutrition/recipe books: https://myunexpectedguide.blogspot.com/2024/02/best-nutrition-on-recipe-books.html



Thursday, 8 May 2025

Our latest issue of Flourish magazine is out - cancer and art

Issue 6 of our Flourish Magazine - the Mind Issue - is out now - It even includes a photo submission by myself! 
Since I helped set up this magazine I've seen it grow and develop to include some great workshops with different communities including parts of the magazine being printed in Somali and Urdu. All credit to Artlift for developing and taking a lead with all this - and Natalie our editor who pulls it all together into such a beautiful magazine.

Flourish Magazine is a joint venture between integrative cancer care charity Yes to Life and creative health charity Artlift supported by funding from various sources including the Arts Council England. The Magazine aims to explore the benefits of an integrative and creative approach to living with cancer. The magazine is created with the support of our steering group that includes people living with cancer and partners Gloucestershire Health and Care NHS Foundation Trust. Each themed edition features a range of creative responses, expert information and interviews that offer support and represent the diversity of the cancer community.

See latest issue and past issues at: https://artlift.org/artlift-programmes/flourish/flourish-magazine/

Thursday, 27 March 2025

Now at number 19 in top prostate cancer blogs

Up to position 19 from number 26 last year of cancer blogs on FeedSpot - ranked by traffic, social media followers and freshness. It is great to hear as I've not been so active re the blog this year - having said that I've still managed to post fairly regularly and also get nice feedback from readers. Thank you! Check out the other blogs at: https://cancer.feedspot.com/prostate_cancer_blogs/ 

As I noted last year most of the blogs seem to be linked to organisations or products and it looks like very few take a focus of integrative health ie getting the best from conventional, lifestyle and complimentary approaches. 

Monday, 17 March 2025

Taking aspirin for cancer?

Several years ago I helped host an online Forum with Yes to Life looking at the evidence around aspirin - this led to Yes to Life publishing a leaflet to raise awareness about the possible benefits and trials - see here: https://yestolife.org.uk/resource/low-dose-aspirin-and-cancer-treatment/

There was also a radio show with Yes to Life's Robin Daly interviewing two doctors researching it - see here: https://ukhealthradio.com/blog/episode/safe-effective-and-cheap-prof-peter-elwood-and-dr-gareth-morgan-present-their-latest-findings-on-the-use-of-aspirin-in-cancer-treatment/

Some six months ago I started taking 75mg of aspirin. I am aware that long term low dose usage is where there is growing evidence of its impact - it was good to see research published in Nature out this month is now starting to understand how aspirin works. Positive News reported on the latest research:

Scientists believe that they have worked out how aspirin stops some cancers from spreading. Studies of people with cancer have previously observed that those taking daily aspirin have a reduction in metastases – the spread – of some cancers, such as breast, bowel, and prostate cancers. Until now, it wasn’t known how aspirin is able to prevent metastases. But a study by the University of Cambridge, England, suggests that, as cancer starts spreading, there is “a unique therapeutic window of opportunity when cancer cells are particularly vulnerable to immune attack”. Aspirin can help the body launch that immune attack. The discovery could lead to the targeted use of aspirin to prevent the spread of certain cancers, and to the development of more effective drugs to prevent metastasis. However, scientists cautioned that aspirin can cause serious side-effects for some, and that people should consult their doctor before starting to take it. 

Update 29.03.25: Just listening to excellent talk with Prof Joachim Drevs on using aspirin - the talk should be available within a couple of weeks on the Yes to Life website - excellent! Why with all the research is it not standard treatment? Here is the brief about the webinar: "In many clinical studies, Aspirin is well proven for its preventive and adjuvant efficacy in all types of solid cancers. A similar salicylic acid, Diflunisal, has been used by us in a compassionate use programme since 2011. The particular mechanism of action of Diflunisal is highly effective, as demonstrated in patients with various cancer types, where a swift reduction in tumour burden has been observed. Additionally, this treatment has a secondary mode of action involving the immune system. The treatment protocol typically consists of five cycles, each lasting five days, and is generally well-tolerated. Despite its potent anticancer effects, the treatment's safety profile is considered favourable. Preliminary data from a pilot study suggest promising outcomes, with an approximate response rate of >60% for partial or complete remission and around 30% of patients achieving lasting remissions, regardless of tumour origin."

Tuesday, 18 February 2025

Understanding testosterone

As we know blocking testosterone production halts tumour growth in early disease, while elevating the hormone can delay disease progression in patients whose disease has advanced. This never made that much sense....Now it seems we have an explanation: 

"The researchers found that prostate cancer cells are hardwired with a system that allows them to proliferate when the levels of testosterone are very low. But when hormone levels are elevated to resemble those present in the normal prostate, the cancer cells differentiate....It turned out to be rather simple. When androgen levels are low, the androgen receptor is encouraged to “go solo” in the cell. In doing so, it activates the pathways that cause cancer cells to grow and spread. However, as androgens rise, the androgen receptors are forced to “hang out as a couple,” creating a form of the receptor that halts tumor growth. Nature has designed a system where low doses of hormones stimulate cancer cell proliferation and high doses cause differentiation and suppress growth, enabling the same hormone to perform diverse functions."

Here's the research article: https://corporate.dukehealth.org/news/study-solves-testosterones-paradoxical-effects-prostate-cancer

Here's also Chris Woollams at Canceractive writing in 2020 about hormone treatment (before this recent discovery). His article is an interesting look at current practice and a possibly different approach to hormones: https://www.canceractive.com/article/the-reality-of-lowered-testosterone-and-higher-oestrogen-in-men-counters-orthodox-theories-of-prostate-cancer He concludes rather grimly: "It all really seems a bit of a mess. Low Testosterone makes matters worse and standard treatment is to cut testosterone! Blood fat levels make matters worse, and standard treatment raises them! Anti-oestrogens seem to do a good job and no oncologist thinks to explore an anti-oestrogen, or indole 3 carbinol, or melatonin?. Meanwhile the number of prostate deaths climb, and recurrence is a major factor. As a friend of mine with a prostate cancer a decade ago said 'there doesn't seem to be best practice in prostate cancer'. He could well be right."

We still have a way to go - the latest research is very useful in helping us understand.

Update May 2025: An article by Dr Geo Espinosa at X Wellness (May 2025) concluded: "At best, there is a weak link between testosterone and prostate cancer, but that is primarily based on test tube and animal studies. Well-performed human studies suggest that if there is any link between the two, low testosterone might increase the risk of prostate cancer, not the reverse. It would be a good idea to have an honest and open discussion about testosterone and prostate cancer with your physician at your next medical visit and learn how you can optimize your testosterone levels after prostate cancer. A conversation on TT in men on Androgen Deprivation Therapy (ADT) is mute since the medical approach intends to lower testosterone to minimize androgen receptor (AR) production. There again, testosterone is not the villain, but the AR's might be. "

Monday, 10 February 2025

Sunday, 9 February 2025

Inspire2Live

What a great name for an organisation, Inspire2Live - I joined them as a patient advocate several years ago now - we are some 100 patient advocates from dozens of countries around the world. The group meets online every week and in person at conferences - sadly I've been only on the edges of this group as meeting times are a challenge. However it is great to see this group making real tangible changes - see Peter Kapitein at a recent conference - he was the guy that started this all off: https://www.youtube.com/watch?v=tkHeAJ9jUVo

Check out Inspire2Live at: https://inspire2live.org/

And here are the advocates from around the World: https://inspire2live.org/about-us/patient-advocacy/meet-our-patient-advocates/

PSA levels in 2 studies found not to reflect prostate cancer growth

Thanks to a blog at 'Dan's Journey through Prostate Cancer' I saw this interesting piece of research into PSA levels. The Corne...