I think this is a useful article looking at chemo from The Life Organic blog by Dale Atkinson (Stage IV cancer); 'Chemotherapy: what it can cure, what it can’t, and what we have to own after the drip stops' https://thelifeorganic.com/chemotherapy-what-it-can-cure-what-it-cant-and-what-we-have-to-own-after-the-drip-stops/
The article covers lots more but in terms of prostate cancer here is a brief summary:
Prostate cancer: In metastatic hormone-sensitive disease, chemotherapy can offer survival benefits alongside androgen deprivation, but it is not curative in this metastatic stage. Guidelines and large trials agree on this: https://www.cancer.gov/types/prostate/patient/prostate-treatment-pdq
