The charity Yes to Life brought my attention to this aspect of the major UK study; the STAMPEDE trial. It recently explored whether adding metformin, a commonly used diabetes medication, to hormone therapy could improve outcomes for men starting treatment for advanced prostate cancer.
The results were not a simple yes or no.
As Yes to Life note "the study did not show a clear improvement in overall survival for most people. But it did show something quieter, and still important. Metformin helped reduce some of the physical strain that hormone therapy can place on the body, including weight gain and changes to blood sugar and cholesterol."
This is a wonderful reminder that care is not only about the tumour. It is about the whole person. The body that is carrying the treatment.
Yes to Life write: "It is also a reminder of why evidence matters. Integrative support should never be about quick fixes or promises. It should be about thoughtful, well-informed care that works alongside medical treatment, not instead of it."
If you would like to read the full article, you can find it here: https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(25)00231-1/fulltext
It is also worth mentioning that Metformin maybe takes a key role in the treatment of other cancers using off-label drugs and others to 'starve' the cancer. See more about that at: https://myunexpectedguide.blogspot.com/2018/09/can-we-starve-our-cancer.html

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